Setting MS Search position

There are two modes of work available in Clarity - using libraries (typical to GC-MS applications) or not using them (typical to LC-MS applications). Some of the MS Extension features may not be available without the spectral libraries usage (spectra matches, conformity etc.), however the use of spectral libraries is not mandatory.

• If you want to use spectrum identification features, Clarity expects that any compound defined in the MS method is identified in the MS Library, either in a commercial one or a user-created library. Clarity works with NIST Libraries and saves the files in NIST-compatible format. A small Demo_MS library is installed by default in C:\CLARITY\DataFiles\Nist directory. If you already have NIST Libraries installed, we recommend using them, as they usually contain more spectra. Typical placement of the NIST Libraries is in the C:\NistXX folder.
• During the first opening of the Instrument window set as LC-MS or GC-MS, Clarity will automatically select the default location of the MS Library, for default Clarity installation located in (\CLARITY\DataFiles\Nist folder).

• You can later change the location of the libraries by using the MS – Set NIST Libraries Directory… command from the MS Chromatogram window.