Setting MS Search position

There are two modes of work available in Clarity - using libraries (typical to GC-MS applications) or not using them (typical to LC-MS applications). Some of the MS Extension features may not be available without the spectral libraries usage (spectra matches, conformities etc.), however the use of spectral libraries is not mandatory.

• If you want to use spectrum identification features, Clarity expects that any compound defined in the MS method is identified in the MS Library, be it a commercial one or a library self-made by the user. Clarity cooperates with the NIST Libraries and also saves the files in NIST-compatible format. A small Demo_MS library is pre-created in the installation of the Clarity, saved in the folder in C:\CLARITY\DataFiles\Nist directory. If you already have NIST Libraries installed, we would strongly recommend to use those libraries instead as they are probably more rich. Typical placement of the NIST Libraries is in the C:\NistXX folder.
• During the first opening of the Instrument window set as LC-MS or GC-MS, Clarity will automatically select the default location of the MS Library, for default Clarity installation located in (\CLARITY\DataFiles\Nist folder).

• You can later change the location of the libraries by using the MS – Set NIST Libraries Directory… command from the MS Chromatogram window.